@article{oai:osaka-aoyama.repo.nii.ac.jp:00000042, author = {奥, 和之 and 田中, 彩乃 and 小山, かおる and 川西, 美穂 and 坂, 江理香 and 藤原, 政嘉}, journal = {大阪青山大学紀要, Journal of Osaka Aoyama University}, month = {Mar}, note = {Dahlia tuber extract are a good source of inulin, a soluble dietary fiber, comparable to other inulin-rich foods such as Jerusalem artichoke, chicory and edible burdock. In the present study, the effect of a dahlia tuber extract on sugar tolerance was examined. The dahlia tuber extract showed weak inhibition against α-glucosidases, inhibiting the activity of maltase in hog intestinal mucosa with an IC50 of 73mM vs 1.7 mM for acarbose. Kinetic analysis revealed that the dahlia tuber extract behaved like a mixed non-competitive type inhibitor with a Ki value of 108mM.Oral sugar tolerance tests in healthy rats showed that administration of the dahlia tuber extract along with maltodextrin suppressed the postprandial increase in blood glucose. The ameliorating effect of the dahlia tuber extract on sugar intolerance in the normal rats was considered to be mainly due to its α-glucosidases inhibitory activity.}, pages = {71--75}, title = {ダリア球根抽出物の食後血糖上昇抑制作用}, volume = {4}, year = {2012}, yomi = {オク, カズユキ and タナカ, アヤノ and コヤマ, カオル and カワニシ, ミホ and サカ, エリカ and フジワラ, マサヨシ} }