@article{oai:osaka-aoyama.repo.nii.ac.jp:00000008,
 author = {石橋, 文秀 and 森藤, 昌樹 and 根来, 千晴 and 園田, 章 and 片山, あずさ and 武部, 靖},
 journal = {大阪青山大学紀要, Journal of Osaka Aoyama University},
 month = {Mar},
 note = {40017377550, 5-chlorosulfonyl-2-oxobenzimidazole(１) was synthesized. 　On adding １ to the suspension of papain in acetonitrile containing formamide, １ was introduced into the papain in a yield of 7%, suggesting that １ modified papain chemically to give 2-oxobenzimidazolesulfonyl papain(OBI- papain). 　Also, it was found in-terestingly that papain activity of OBI-papain was maintained and that SH group in the active center in the large cleft of papain was free. 　Accordingly, It expects that OBI-papain might have other catalytic action except pa-pain activity. (accepted. Dec. 12, 2008)},
 pages = {35--38},
 title = {Studies on chemical modification of papain by 5-chlorosulfonyl-2-oxobenzimidazole as biotin model compound},
 volume = {1},
 year = {2009}
}